BioExcel

Powering biomolecular research through advanced computing

Author: Arno Proeme
Posted: 25 Jun 2019 | 15:51

BioExcel is a Centre of Excellence that supports academic and industrial researchers in the use of advanced computing in biomolecular research. It has received follow-on Horizon 2020 funding from the EU Commission to continue and expand its activities for a period of three years starting from January 2019.

Spark-based genome analysis on Cray-Urika and Cirrus clusters

Author: Rosa Filgueira
Posted: 16 Jan 2019 | 11:06

Analysing genomics data is a complex and compute intensive task, generally requiring numerous software tools and large reference data sets, tied together in successive stages of data transformation and visualisation.

Typically in a cancer genomics analysis, both a tumour sample and a “normal” sample from the same individual are first sequenced using NGS systems and compared using a series of quality control stages. The first control stage, ‘Sequence Quality Control’ (which is optional), checks sequence quality and performs some trimming. While the second one, ‘Alignment’, involves a number of steps, such as alignment, indexing, and recalibration, to ensure that the alignment files produced are of the highest quality as well as several more to guarantee the variants are called correctly. Both stages compromise a series of intermediately computing and data-intensive steps that very often are handcrafted by researchers and/or analysts.

Building a Centre of Excellence for computational biomolecular research

Author: Adam Carter
Posted: 15 Jun 2017 | 11:59

The BioExcel project, which is establishing a Centre of Excellence in Computational Biomolecular Research, is now well into its second year. Here is an update on our progress.

Forthcoming computational biomolecular research events

Author: Adam Carter
Posted: 9 Aug 2016 | 17:18

BioExcel is a newly launched Centre of Excellence that helps academic and industrial researchers to use high-performance computing and high-throughput computing in biomolecular research. 

We are running a number of events in September and October and I would be very grateful to anybody who circulates these to people or groups that may be interested (and bonus points if you are willing to share with me details of where/to whom you publicise so that we can reduce cross-posting).

 

Blog Archive